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Order Spironolactone (generic Spironolactone)
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| Brand Name | Spironolactone |
| Generic Name | Spironolactone |
| Category | Blood Pressure |
| Medication | 25, 50 and 100 mg |
What is Spironolactone (Generic Spironolactone) and what are its uses?
Spironolactone is a potassium-sparing diuretic.
Spironolactone is commonly used in conditions such as heart failure, where the pumping mechanism of the heart is less effective. Spironolactone is used to relieve the symptoms of heart failure, such as the shortness of breath seen with fluid on the lungs. Spironolactone is also used to remove excess fluid associated with liver failure, as well as in the treatment of excessive levels of aldosterone (hyperaldosteronism).
Spironolactone does not increase the loss of potassium from the body in the urine, therefore there is less risk of developing low potassium levels in the blood (hypokalaemia).
When Spironolactone is used alone it has a weak effect, therefore it is often used in combination with other diuretics.
How does Spironolactone (Generic Spironolactone) treat?
Spironolactone belongs to a group of medications known as the potassium-sparing diuretics.
Spironolactone acts in the kidney to remove excess water from the blood into the urine.
Spironolactone blocks the actions of a hormone called aldosterone, which causes an increase in the removal of salts such as sodium from the blood. This removal of salts causes water to be drawn out of the blood and into the kidneys, where it is then excreted in the urine. Removing water from the blood causes a decrease in the volume of fluid circulating through the blood vessels. This drop in fluid volume decreases the effort required by the heart to pump blood around the body.
Dosage: How should you take Spironolactone (Generic Spironolactone)?
Fluid Retention (Congestive Heart Failure, Cirrhosis of the Liver, or Kidney Disorders)
The usual starting dose of Spironolactone is 100 milligrams daily either in a single dose or divided into smaller doses. However, your doctor may have you take daily doses as low as 25 milligrams or as high as 200 milligrams.
Your doctor may choose to adjust your dosage after an initial 5-day trial period or add another diuretic medication to this one.
Essential Hypertension (High Blood Pressure)
The usual starting dose of Spironolactone is 50 to 100 milligrams daily in a single dose or divided into smaller doses. Spironolactone may be given with another diuretic or with other high blood pressure medications.
It may be up to 2 weeks before the full effect of Spironolactone is seen. Your doctor can then adjust the dosage according to your response.
Hypokalemia (Potassium Loss)
Your doctor may have you take daily doses of 25 milligrams to 100 milligrams when potassium loss caused by the effects of a diuretic cannot be treated by a potassium supplement.
Symptoms that are likely to occur with Spironolactone overdose are
Store Spironolactone at room temperature below 30 degrees C (86 degrees F). Throw away any unused amount of Spironolactone after the expiration date.
Effect of other drugs consumed with Spironolactone (Generic Spironolactone)
The following drugs may interact with Spironolactone. They may increase or decrease the activity of Spironolactone
Inform your health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way Spironolactone works. Check with your health care professional before stopping or starting any of your medicines.
Who should not take Spironolactone?
Spironolactone should not be used if you suffer from sudden decrease in kidney function (acute renal insufficiency), severe and worsening kidney disease, high levels of potassium in the blood (hyperkalemia) and failure of kidneys to produce urine.
Spironolactone should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
If you feel you have experienced an allergic reaction, stop using Spironolactone and inform your doctor or pharmacist immediately.
The effects of Spironolactone during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Spironolactone appears in breast milk and could affect a nursing infant. If Spironolactone is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with Spironolactone is finished.
What should you watch for while taking Spironolactone (Generic Spironolactone)?
Check your blood pressure regularly. Ask your prescriber or health care professional what your blood pressure should be, and when you should contact him or her. You must not get dehydrated; ask your prescriber or health care professional how much fluid you need to drink a day. Do not stop taking Spironolactone except on your prescriber's advice.
Watch your diet while you are taking Spironolactone. Ask your prescriber or health care professional about both potassium and sodium intake. Spironolactone can make your body retain potassium and you may have too much. Elderly patients, the severely ill, diabetics, or patients with kidney problems are more likely to suffer from the effects of too much potassium. Avoid salt-substitutes and nutritional supplements, which contain potassium, unless your prescriber or health care professional tells you otherwise. Too much potassium can be very harmful. You may need to avoid foods that are high in potassium such as bananas, coconuts, dates, figs, prunes, apricots, peaches, grapefruit juice, tomato juice, and orange juice.
If you are going to have surgery, tell your prescriber or health care professional that you are taking Spironolactone.
Possible Side effects of Spironolactone (Generic Spironolactone)
Side effects of Spironolactone that should be reported to your prescriber or health care professional as soon as possible:
Side effects of Spironolactone that usually do not require medical attention: