Order Generic Combivir (Buy Lamivudine-Zidovudine)

Brand Name Combivir
Generic Name Lamivudine-Zidovudine
Category Antiviral
Medication 150/300 mg

Information to have about Lamivudine-Zidovudine (Generic Equivalent to Combivir) . .

What is Lamivudine-Zidovudine (Generic Combivir) and what are its uses ?
How does Lamivudine-Zidovudine (Generic Combivir) Works (Mechanism) ?
Dosage: How should you take Lamivudine-Zidovudine (Generic Combivir) ?
Possible food and drug interactions when taking Lamivudine-Zidovudine (Generic Combivir)
Lamivudine-Zidovudine (Generic Combivir) Warnings and Precautions
Lamivudine-Zidovudine (Generic Combivir) Side effects

Order Lamivudine-Zidovudine - Generic Equivalent to Combivir
Category : Antiviral
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What is Lamivudine-Zidovudine (Generic Combivir) and what are its uses ?

Combivir is a combination of two antiviral drugs Zidovudine and Lamivudine in one tablet.

Combivir can slow down the damage caused by the human immunodeficiency virus (HIV), the virus that causes acquired immune deficiency syndrome (AIDS). The amount of HIV virus in the blood is called "viral load."

Combivir can reduce the viral load, especially when combined with another anti-HIV drug. Combivir will not cure or prevent HIV infection or AIDS.

How does Lamivudine-Zidovudine (Generic Combivir) Works (Mechanism) ?

Combivir contains two active ingredients, zidovudine and lamivudine. These are both medicines called nucleoside reverse transcriptase inhibitors.

Combivir is used in the treatment of HIV (human immunodeficiency virus) infection.

AIDS (acquired immune deficiency syndrome) is caused by infection with HIV. This virus invades cells of the immune system, particularly the white blood cells known as CD4 T-helper lymphocytes. These cells normally work to activate other cells in the immune system to fight infection. Since HIV kills CD4 T-helper cells, over time the body becomes less able to fight the virus or subsequent infections.

Once the virus is inside the CD4 T-cell it multiplies. Part of the process of viral multiplication involves the conversion of the virus genetic material, RNA, into DNA. This is achieved by a compound essential to the virus, called reverse transcriptase. Reverse transcriptase is a compound known as an enzyme. Combivir works by blocking the action of this enzyme, thereby interfering with the conversion of viral RNA into DNA. This stops the virus from multiplying.

There is no cure for HIV, but Combivir is one of the medications that lowers the amount of virus in the body (viral load) and slows the progression of the disease from HIV to AIDS. 

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Dosage: How should you take Lamivudine-Zidovudine (Generic Combivir) ?

Take Combivir tablets orally. Swallow the tablets with a drink of water. You can take Combivir with or without food. Take your doses at regular intervals. It is very important that you take Combivir exactly as instructed by your prescriber or health care professional.

Adults
The usual prescribed dose of Combivir 150/300 mg is one tablet taken twice a day.

Children
Contact your pediatrician or health care professional regarding the use of Combivir in children. Special care may be needed.

Have you skipped your Combivir dose?
If you miss a dose of Combivir, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses of Combivir.

If you take too much of Combivir?
Incase of an overdose with Combivir seek medical emergency immediately.

Symptoms of Combivir overdose include

  • nausea,
  • vomiting,
  • headache,
  • dizziness,
  • drowsiness,
  • lethargy,
  • confusion, and
  • seizures.
Where should you store Combivir?

Keep Combivir out of the reach of children in a container that small children cannot open.

Store Combivir between 20 and 30 degrees C. Keep the container tightly closed. Throw away any unused amount of Combivir after the expiration date.

Available strengths of Combivir
Combivir tablets are available in the strength of 150/300 mg (Lamivudine 150 mg+ Zidovudine 300 mg).

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Possible food and drug interactions when taking Lamivudine-Zidovudine (Generic Combivir)

The following drugs may interact with Combivir. They may increase or decrease the activity of Combivir

  • atovaquone
  • fluconazole
  • interferon
  • probenecid
  • valproic acid
  • zalcitabine, ddC

Inform your health care professional about all other medicines you are taking, including nonprescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way Combivir works. Check with your health care professional before stopping or starting any of your medicines.

Who should not take Combivir?

Combivir should not be used by people with low levels of a type of white blood cell (neutrophil) in the blood and by those suffering from anaemia.

Combivir should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.

If you feel you have experienced an allergic reaction, stop using Combivir and inform your doctor or pharmacist immediately

Lamivudine-Zidovudine (Generic Combivir) Warnings and Precautions

You must visit your prescriber or health care professional for regular checks on your progress. Combivir will not cure HIV infection and you can still get other illnesses associated with HIV.

Tell your prescriber or health care professional if you get tingling, pain or numbness in your hands or feet.

Tell your prescriber or health care professional at once if you have nausea and vomiting accompanied by severe stomach pain.

Combivir can cause blood problems. This can mean slow healing and a risk of infection. Try to avoid cutting or injuring yourself. Problems can arise if you need dental work, and in the day to day care of your teeth. Try to avoid damage to your teeth and gums when you brush or floss your teeth. Your prescriber or health care professional will check your blood counts while you are receiving Combivir. It is very important that you keep any appointments that are scheduled by your prescriber or health care professional.

Taking Combivir does not reduce the risk of passing HIV infection to others through sexual or blood contact. It is best to avoid sexual contact so that you do not spread the disease to others. For any sexual contact, use a condom. Be careful about cuts, abrasions and other possible sources of blood contact. Never share a needle or syringe with anyone.

Lamivudine-Zidovudine (Generic Combivir) Side effects

Side effects of Combivir that should be reported to your prescriber or health care professional as soon as possible:

  • depression
  • dizziness
  • fever or chills, sore throat
  • loss of appetite
  • muscle pain or weakness
  • nausea, vomiting
  • pain, tingling, or numbness in the hands or feet
  • shortness of breath
  • unusual bleeding or bruising
  • unusual tiredness or weakness

Side effects of Combivir that should be reported to your prescriber or health care professional if they continue or are bothersome:

  • change in nail color
  • cough
  • diarrhea
  • difficulty sleeping
  • headache
  • runny or stuffy nose
  • skin rash
  • tiredness
  • upset stomach