
| Brand Name | Avandia |
| Generic Name | Rosiglitazone Maleate |
| Category | Diabetes |
| Medication | 2, 4 and 8 mg |
What is Rosiglitazone Maleate (Generic Avandia) and what are its uses?
Rosiglitazone Maleate (Generic Avandia) is an antihyperglycemic agent.
Rosiglitazone Maleate (Generic Avandia) helps the body respond better to insulin and it reduces the amount of sugar produced by the liver. Rosiglitazone Maleate (Generic Avandia) thereby helps control blood sugar levels.
Rosiglitazone Maleate (Generic Avandia) is used, along with diet and exercise, in the treatment of type 2 diabetes. Rosiglitazone Maleate (Generic Avandia) may also be used with a sulfonylurea, metformin (Glucophage), or insulin when diet and exercise plus any one of these medicines alone do not result in adequate blood sugar control.
How does Rosiglitazone Maleate (Generic Avandia) treat?
Rosiglitazone Maleate (Generic Avandia) tablets contain the active ingredient rosiglitazone maleate, which is an antidiabetic medicine used to treat people with type 2 or non-insulin dependent diabetes (NIDDM). In this type of diabetes the cells of the body are resistant to the low levels of insulin circulating in the blood. Insulin would normally make the cells remove sugar from the blood.
Rosiglitazone Maleate (Generic Avandia) helps to lower blood sugar levels by increasing the sensitivity of liver, fat and muscle cells to insulin. This enables these cells to remove sugar from the blood more effectively.
Rosiglitazone Maleate (Generic Avandia) also preserves the functioning of the cells in the pancreas (beta cells) that produce insulin. The overall effect of this medicine is therefore to help the body control blood sugar levels and prevent them becoming too high.
Rosiglitazone Maleate (Generic Avandia) can also used for people with type 2 diabetes whose blood sugar is not controlled by the maximum doses of either metformin, or another type of antidiabetic medicine known as a sulphonylurea. In these cases Rosiglitazone Maleate (Generic Avandia) is added to treatment with the oral antidiabetic already being taken.
Dosage: How should you take Rosiglitazone Maleate (Generic Avandia)?
Take Rosiglitazone Maleate (Generic Avandia) tablets orally.
Swallow Rosiglitazone Maleate (Generic Avandia) tablets with a drink of water with meals.
If your sugar levels still continue to remain too high after 12 weeks of treatment, the doctor may increase your dose of Rosiglitazone Maleate (Generic Avandia) to 8 milligrams once a day or 4 milligrams twice a day.
Rosiglitazone Maleate (Generic Avandia) Dosage for Children
Rosiglitazone Maleate (Generic Avandia)is not recommended for children under 18.
However, contact your pediatrician or health care professional regarding the use of Rosiglitazone Maleate (Generic Avandia) in children if required to be used. Special care may be needed.
Where should you store Rosiglitazone Maleate (Generic Avandia)?
Keep Rosiglitazone Maleate (Generic Avandia) out of the reach of children in a container that small children cannot open.
Store Rosiglitazone Maleate (Generic Avandia) at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Keep container tightly closed and protect from light. Throw away any unused amount of Rosiglitazone Maleate (Generic Avandia) after the expiration date.
Effect of other drugs consumed with Rosiglitazone Maleate (Generic Avandia)
The following drugs may interact with Rosiglitazone Maleate (Generic Avandia). They may increase or decrease the action of Rosiglitazone Maleate (Generic Avandia)
Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way Rosiglitazone Maleate (Generic Avandia) works. Check with your health care professional before stopping or starting any of your medicines.
Who should not take Rosiglitazone Maleate (Generic Avandia)?
If you have liver disease, you should not take Rosiglitazone Maleate (Generic Avandia). Your doctor will check to make sure your liver function is normal before prescribing Rosiglitazone Maleate (Generic Avandia), and then recheck it every 2 months for the first 12 months and periodically thereafter. Warning signs of liver damage include nausea, vomiting, abdominal pain, fatigue, loss of appetite, and dark urine. If you develop any of these symptoms, tell your doctor immediately. You may need to discontinue treatment with Rosiglitazone Maleate (Generic Avandia).
People taking Rosiglitazone Maleate (Generic Avandia) in combination with other diabetes drugs sometimes develop low blood sugar. If this happens, check with your doctor. The dosage of the other diabetes drug may have to be reduced.
People with kidney problems can take Rosiglitazone Maleate (Generic Avandia), but should not take Glucophage. If you have poor kidney function, you'll be unable to take advantage of this combination.
Rosiglitazone Maleate (Generic Avandia) can increase the chances of conception. Be sure to use some form of birth control if you do not want a pregnancy.
Rosiglitazone Maleate (Generic Avandia) will not help type 1 diabetics, who are unable to produce any insulin at all. Insulin shots are a necessity for this form of the illness. Rosiglitazone Maleate (Generic Avandia) will not relieve diabetic ketoacidosis (excessively high sugar levels due to lack of insulin).
Use Rosiglitazone Maleate (Generic Avandia) with caution if you have a problem with fluid retention or swelling. The drug has been known to cause this problem, which in turn can lead to heart failure. Rosiglitazone Maleate (Generic Avandia) should be avoided by anyone who has been diagnosed with heart failure, and it should be discontinued by anyone who develops it. Make sure the doctor is aware of any heart problems you may have. Alert him immediately if you develop symptoms of heart failure such as fatigue and shortness of breath.
You should be aware that people taking Rosiglitazone Maleate (Generic Avandia) tend to gain a little weight, typically around 5 to 10 pounds. The cause is thought to be a combination of fluid retention and fat accumulation.
It's important to maintain normal blood sugar levels while pregnant, but the safety of Rosiglitazone Maleate (Generic Avandia) during pregnancy remains unproven. Since insulin shots are known to be safe, your doctor may switch you from Rosiglitazone Maleate (Generic Avandia) to insulin until the baby is born.
It is not known whether Rosiglitazone Maleate (Generic Avandia) appears in breast milk. Because many drugs do find their way into breast milk, however, it's safe to avoid taking Rosiglitazone Maleate (Generic Avandia) while nursing.
What should you watch for while taking Rosiglitazone Maleate (Generic Avandia)?
Visit your prescriber or health care professional for regular checks on your progress. Learn how to monitor blood or urine sugar and urine ketones regularly. Check with your prescriber or health care professional if your blood sugar is high, you may need a change of dose of Rosiglitazone Maleate (Generic Avandia).
Do not skip meals. If you are exercising much more than usual you may need extra snacks to avoid Side effects of Rosiglitazone Maleate (Generic Avandia) caused by low blood sugar.
If you have mild symptoms of low blood sugar, eat or drink something containing sugar at once and contact your prescriber or health care professional. It is wise to check your blood sugar to confirm that it is low. It is important to recognize your own symptoms of low blood sugar so that you can treat them quickly. Make sure family members know that you can choke if you eat or drink when you have serious symptoms of low V, such as seizures or unconsciousness. They must get medical help at once.
If you are going to have surgery, tell your prescriber or health care professional that you are taking Rosiglitazone Maleate (Generic Avandia).
Possible Side effects of Rosiglitazone Maleate (Generic Avandia)
Side effects of Rosiglitazone Maleate (Generic Avandia) that you should report to your prescriber or health care professional as soon as possible:
Side effects of Rosiglitazone Maleate (Generic Avandia) that usually do not require medical attention:
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