Brand Name	Bactrim DS
Generic Name	Sulphamethoxazole-TMP
Category	Antibiotic/ Anti-infectives
Medication	400/80 and 800/160 mg

Information to have about Sulphamethoxazole-TMP (Generic Equivalent to Bactrim DS)

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What is Sulphamethoxazole-TMP (generic Bactrim DS) and what are its uses?
How does Sulphamethoxazole-TMP (generic Bactrim DS) treat?
Dosage: How should you take Sulphamethoxazole-TMP (generic Bactrim DS)?
Effect of other drugs consumed with Sulphamethoxazole-TMP (generic Bactrim DS)
What should you watch for while taking Sulphamethoxazole-TMP (generic Bactrim DS)?
Possible Side effects of Sulphamethoxazole-TMP (generic Bactrim DS)

Order Sulphamethoxazole-TMP - Generic Equivalent to Bactrim DS
Category :	Antibiotic/Anti-infectives
Medication	Quantity	Price USD	Order
Bactrim Brand 400/80 mg Generic Equivalent to Bactrim Brand 400/80 mg	60	0.43	Order Bactrim Brand 400/80 mg
Bactrim Brand 400/80 mg Generic Equivalent to Bactrim Brand 400/80 mg	120	0.42	Order Bactrim Brand 400/80 mg
Bactrim Brand 400/80 mg Generic Equivalent to Bactrim Brand 400/80 mg	180	0.41	Order Bactrim Brand 400/80 mg
Bactrim Brand 400/80 mg Generic Equivalent to Bactrim Brand 400/80 mg	240	0.40	Order Bactrim Brand 400/80 mg
Bactrim Brand 400/80 mg Generic Equivalent to Bactrim Brand 400/80 mg	300	0.39	Order Bactrim Brand 400/80 mg
Medication	Quantity	Price USD	Order
Bactrim DS Brand 800/160 mg Generic Equivalent to Bactrim DS Brand 800/160 mg	60	0.53	Order Bactrim DS Brand 800/160 mg
Bactrim DS Brand 800/160 mg Generic Equivalent to Bactrim DS Brand 800/160 mg	120	0.52	Order Bactrim DS Brand 800/160 mg
Bactrim DS Brand 800/160 mg Generic Equivalent to Bactrim DS Brand 800/160 mg	180	0.51	Order Bactrim DS Brand 800/160 mg
Bactrim DS Brand 800/160 mg Generic Equivalent to Bactrim DS Brand 800/160 mg	240	0.49	Order Bactrim DS Brand 800/160 mg
Bactrim DS Brand 800/160 mg Generic Equivalent to Bactrim DS Brand 800/160 mg	300	0.48	Order Bactrim DS Brand 800/160 mg

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What is Sulphamethoxazole-TMP (generic Bactrim DS) and what are its uses?

Bactrim DS is a combination of two antibiotics.

Bactrim DS is used to treat infections of the urinary tract, middle ear, and respiratory tract (bronchitis).

Bactrim DS is also used for traveler's diarrhea, and Pneumocystis carinii pneumonia in AIDS or cancer patients.

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How does Sulphamethoxazole-TMP (generic Bactrim DS) treat?

Bactrim DS tablets contain Trimethoprim and sulfamethoxazole. Sulfamethoxazole belongs to the sulphonamide group of antibiotics.

Trimethoprim and sulfamethoxazole both work inside the bacterial cell, where they stop the manufacture of a substance called folic acid. Folic acid is necessary for the production of genetic material (DNA). Without the production of DNA the bacteria is not able to reproduce, and the spread of the infection is stopped (a bacteriostatic effect).

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Dosage: How should you take Sulphamethoxazole-TMP (generic Bactrim DS)?

Take Bactrim tablets orally.

Follow the directions on the prescription label. Take Bactrim tablets with a full glass of water. Take your doses at regular intervals. Do not take Bactrim more often than directed.

Adults

Urinary Tract Infections and Intestinal Inflammation
The usual prescribed dose of Bactrim DS in the treatment of urinary tract infection is 1 tablet every 12 hours for 10 to 14 days. The dose of Bactrim DS for inflammation of the intestine is the same but is taken for 5 days.

Worsening of Chronic Bronchitis
The usual recommended dose of Bactrim DS is 1 tablet every 12 hours for 14 days.

Treatment of Pneumocystis Carinii Pneumonia
The recommended dosage is 15 to 20 milligrams of Trimethoprim and 75 to 100 milligrams of sulfamethoxazole per 2.2 pounds of body weight per 24 hours divided into equal doses every 6 hours for 14 to 21 days.

Prevention of Pneumocystis Carinii Pneumonia
The recommended dose of Bactrim DS is 1 tablet once daily.

Travelers' Diarrhea
The usual recommended dose of Bactrim DS is 1 tablet every 12 hours for 5 days.

Children
The recommended dose of Bactrim DS for children 2 months of age or older, given every 12 hours for 10 days, is determined by weight.

Prevention of Pneumocystis Carinii Pneumonia
The recommended dose of Bactrim DS, taken twice a day, on 3 consecutive days per week, is determined by body surface area. The total daily dose of Bactrim DS should not exceed 320 milligrams Trimethoprim and 1600 milligrams sulfamethoxazole.

The safety of repeated use of Bactrim DS in children under 2 years of age has not been established.

Older Adults
There may be an increased risk of severe side effects when Bactrim DS is taken by older people, especially in those who have impaired kidney and/or liver function or who are taking other medication. Consult with your doctor before taking Bactrim DS .

Have you skipped your Bactrim dose?
If you miss a dose of Bactrim DS, take it as soon as you can. If it is almost time for your next dose of Bactrim DS, take only that dose. Do not take double or extra doses of Bactrim DS. You must leave a suitable interval between doses. If you are taking one dose of Bactrim DS a day and have to take a missed dose, make sure there is at least 10 to 12 hours between doses. If you are taking two doses a day and have to take a missed dose, make sure there is at least 5 to 6 hours between doses.

If you take too much of Bactrim?
Incase of an overdose with Bactrim seek medical emergency immediately.

Symptoms of Bactrim overdose include

• blood or sediment in the urine,
• colic,
• confusion,
• dizziness,
• drowsiness,
• fever,
• headache,
• lack or loss of appetite,
• mental depression,
• nausea,
• unconsciousness,
• vomiting,
• yellowed eyes and skin

Where should you store Bactrim?
Store Bactrim DS tablets out of the reach of children in a container that small children cannot open.

Store Bactrim DS at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Protect from light and moisture. Throw away any unused amount of Bactrim DS after the expiry date.

Available strengths of Bactrim
Bactrim is available as a 400/80 mg tablet and Bactrim DS is available as a 800/160 mg tablet.

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Effect of other drugs consumed with Sulphamethoxazole-TMP (generic Bactrim DS)

The following drugs may interact with Bactrim DS. They may increase or decrease the activity of Bactrim DS

• amiloride
• cyclosporine
• dapsone
• digoxin
• divalproex
• dofetilide
• medicines for diabetes
• methenamine
• methotrexate
• metronidazole
• phenytoin
• potassium salts (potassium chloride, potassium phosphate)
• procainamide
• pyrimethamine
• rifampin
• some medicines used to treat blood pressure and/or heart failure (ACE inhibitors such as benazepril, enalapril, lisinopril, moexipril, quinapril, ramipril, and others)
• spironolactone
• sulfinpyrazone
• triamterene
• trimetrexate
• valproic acid
• warfarin

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way Bactrim DS works. Check with your health care professional before stopping or starting any of your medicines.

Who should not take Bactrim?

Bactrim DS should not be used if you suffer from kidney or liver failure.

Bactrim DS should not be used if you suffer from life long inherited blood diseases, which can cause a variety of symptoms, including mental health problems (porphyrias).

Bactrim DS should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.

If you feel you have experienced an allergic reaction, stop using Bactrim DS and inform your doctor or pharmacist immediately

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What should you watch for while taking Sulphamethoxazole-TMP (generic Bactrim DS)?

Inform your health care professional if your symptoms do not improve in 2 to 3 days.

You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how co-trimoxazole affects you.

Keep out of the sun, or wear protective clothing outdoors and use a sunscreen. Do not use sun lamps or sun tanning beds or booths.

Drink several glasses of water a day. This will help to reduce possible kidney problems.

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Possible Side effects of Sulphamethoxazole-TMP (generic Bactrim DS)

Side effects of Bactrim DS that should be reported to your health care professional as soon as possible:

• anemia or other blood disorders
• allergic reactions
• bluish fingernails or lips
• difficulty breathing
• fast or irregular heartbeat, palpitations, chest pain
• fever or chills, sore throat
• increased sensitivity to the sun or ultraviolet light
• joint aches or pains
• lower back pain
• muscle aches or pains
• pain or difficulty passing urine
• redness, blistering, peeling or loosening of the skin, including inside the mouth
• skin rash, hives, or itching
• unusual bleeding or bruising
• unusual weakness or tiredness
• yellowing of the eyes or skin

Side effects of Bactrim DS that should be reported to your health care professional if they continue or are bothersome:

• diarrhea
• dizziness
• headache
• loss of appetite
• nausea, vomiting

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